NEW STERICALLY HINDERED PHENOLS CONTAINING BENZOFUROXAN FRAGMENTS WITH ANTITUMOR ACTIVITY Russian patent published in 2023 - IPC C07D413/14 C07D271/12 A61K31/4245 A61P35/00 

Abstract RU 2796810 C1

FIELD: organic chemistry; medicine.

SUBSTANCE: invention relates to new sterically hindered phenols with fragments of benzofuroxan of general formula I, which can be used as antitumor agents in pharmaceuticals, medicine and veterinary medicine.

EFFECT: new antitumor agents are able to effectively destroy the mitochondria of cells, thereby inhibiting the growth of cancer cells.

2 cl, 2 dwg, 1 tbl, 3 ex

R = Me (a), iPr (b), Ph (c)

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RU 2 796 810 C1

Authors

Chugunova Elena Aleksandrovna

Burilov Aleksandr Romanovich

Gibadullina Elmira Mingaleevna

Voloshina Aleksandra Dmitrievna

Liubina Anna Pavlovna

Amerkhanova Siumbelia Kamilevna

Nguen Khoang Bao Chan

Alabugin Igor Vladimirovich

Matylitskii Kirill Vladimirovich

Dates

2023-05-29Published

2022-10-25Filed