ANTITUMOR AGENTS BASED ON MACRO- AND MICROELEMENT-CONTAINING POLYGALACTURONATES (OPTIONS) Russian patent published in 2023 - IPC A61K31/732 C08B37/06 A61P35/00 

Abstract RU 2792613 C1

FIELD: medicine.

SUBSTANCE: group of inventions refers to a water-soluble agent based on polygalacturonate, which has selective cytotoxic activity against A549 lung carcinoma, MCF-7 breast adenocarcinoma and M-HeLa cervical carcinoma, which is potassium cobalt polygalacturonate (PCCo) or its composition with sodium-cobalt-polygalacturonate (PNaCo) in a mass ratio of 1-2:1-2, and also refers to a water-soluble polygalacturonate-based agent with selective cytotoxic activity against A549 lung carcinoma, MCF-7 breast adenocarcinoma and cervical carcinoma M-HeLa, which is a composition containing sodium-cobalt-polygalacturonate (PNaCo) in a mass ratio of 3:1 and a metal complex of pectin biopolymer sodium-metal-polygalacturonate, respectively, where the biogenic metal is zinc, manganese, chromium or magnesium (PGNaZn, PGNaMn, PGNaCr, PGNaMg).

EFFECT: obtaining antitumor agents based on macro- and microelement-containing polygalacturonates.

2 cl, 1 dwg, 3 tbl

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RU 2 792 613 C1

Authors

Minzanova Salima Takhiiatullovna

Miliukov Vasilii Anatolevich

Chekunkov Evgenii Vladimirovich

Mironova Liubov Gennadevna

Voloshina Aleksandra Dmitrievna

Sapunova Anastasiia Sergeevna

Arkhipova Daria Mikhailovna

Khabibullina Anna Viacheslavovna

Dates

2023-03-22Published

2022-06-23Filed