BROMINE-CONTAINING STERICALLY HINDERED PHENOLS WITH ANTICANCER ACTIVITY Russian patent published in 2024 - IPC C07C39/06 A61K31/05 A61K31/167 A61K31/662 A61P35/00 

Abstract RU 2822270 C1

FIELD: organic chemistry; pharmaceutics.

SUBSTANCE: invention relates to bromine-containing sterically hindered phenols of formula Ia, Ib and Ic, where R is selected from (a) Me, (b) Et and (c) Ph. Invention also relates to the use of a compound of formula I as an agent having anticancer activity.

EFFECT: anticancer compounds of formula I, capable of effectively leading to apoptosis along the internal mitochondrial pathway, thereby inhibiting the growth of cancer cells.

2 cl, 4 dwg, 1 tbl, 3 ex

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RU 2 822 270 C1

Authors

Burilov Aleksandr Romanovich

Gibadullina Elmira Mingaleevna

Voloshina Aleksandra Dmitrievna

Liubina Anna Pavlovna

Sapunova Anastasiia Sergeevna

Chugunova Elena Aleksandrovna

Nguen Khoang Bao Chan

Alabugin Igor Vladimirovich

Shakirov Adel Maratovich

Dates

2024-07-03Published

2023-12-22Filed