DEUTERATED IMIDAZOLIDINEDIONE COMPOUNDS AND THEIR USE Russian patent published in 2023 - IPC A61K31/4166 A61P35/00 

Abstract RU 2798663 C2

FIELD: medicine.

SUBSTANCE: invention can be used to treat prostate cancer. The following is provided: a method of reducing the plasma concentration of prostate specific antigen (PSA) by at least 50% in a subject with an elevated PSA level, comprising administering to the said subject at least 40 mg of HC-1119, wherein the said subject has prostate cancer being any wild-type androgen receptor (AR) positive prostate cancer and mutant AR positive prostate cancer or non-metastatic castration-resistant prostate cancer (nmCRPC).

EFFECT: invention provides effective treatment of specific forms of prostate cancer.

21 cl, 16 dwg, 2 tbl, 12 ex

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RU 2 798 663 C2

Authors

Li, Sinkhaj

Chen, Yuanvej

Dates

2023-06-23Published

2019-03-27Filed