METHOD OF PREDICTING THE RISK OF DEVELOPING ADVERSE CARDIOVASCULAR OUTCOMES WITHIN A YEAR AFTER PERCUTANEOUS CORONARY INTERVENTIONS WITH STENTING IN PATIENTS WITH STABLE CORONARY HEART DISEASE Russian patent published in 2023 - IPC G01N33/74 G01N33/68 G01N33/573 

Abstract RU 2799146 C1

FIELD: medicine, cardiology and cardiac surgery.

SUBSTANCE: invention can be used to predict the risk of adverse cardiovascular outcomes within a year after percutaneous coronary interventions with stenting in patients with stable ischemic heart disease. In patients with stable ischemic heart disease, before the planned implantation of a stent, the content of resistin, leptin and testosterone is determined by enzyme immunoassay. Then the risk of developing adverse outcomes is calculated using the following formula: where K is the predictive coefficient of adverse cardiovascular events, z is the linear regression coefficient calculated by the following formula: z=(-0.025*X1+0.12*X2+0.03*X3-2.66), where -0.025, 0.12, 0.03 - coefficients; -2.66 - constant value obtained by logistic regression, X1 - serum testosterone level in nmol/ml, X2 - serum resistin level in ng / ml, X3 - serum leptin level in ng/ml. When K is greater than or equal to 0.32, a high risk of adverse cardiovascular events is predicted after percutaneous coronary interventions with stenting. When K is less than 0.32, a low risk of developing adverse cardiovascular events after percutaneous coronary interventions with stenting is predicted.

EFFECT: method makes it possible to predict the risk of developing adverse cardiovascular outcomes after percutaneous coronary interventions with stenting in patients with stable coronary artery disease by determining the serum levels of testosterone, leptin, resistin.

1 cl, 1 dwg, 2 tbl, 2 ex

Similar patents RU2799146C1

Title Year Author Number
METHOD FOR ASSESSING THE RISK OF DEVELOPING ADVERSE OUTCOMES WITHIN THE FIRST YEAR FOLLOWING THE PERCUTANEOUS CORONARY INTERVENTION WITH STENTING IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE 2018
  • Orekhova Yuliya Nikolaevna
  • Ivanchenko Darya Nikolaevna
  • Demidova Aleksandra Aleksandrovna
  • Shlyk Sergej Vladimirovich
  • Sizyakina Lyudmila Petrovna
  • Dorofeeva Natalya Petrovna
  • Ter-Akopyan Aleksandra Ovanesovna
  • Chebotova Anastasiya Ivanovna
RU2692257C1
METHOD OF PREDICTING PROBABILITY OF ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH CORONARY HEART DISEASE WHO HAVE UNDERGONE PLANNED CORONARY MYOCARDIAL REVASCULARIZATION 2023
  • Svarovskaia Alla Vladimirovna
  • Astanin Pavel Andreevich
  • Vende Artem Dmitrievich
  • Ogurkova Oksana Nikolaevna
  • Garganeeva Alla Anatolevna
RU2814112C1
METHOD FOR PREDICTING THE RISK OF LATE FATAL CARDIAC AND CEREBROVASCULAR EVENTS AFTER A PLANNED ENDOVASCULAR MYOCARDIAL REVASCULARIZATION 2018
  • Vershinina Elena Olegovna
  • Repin Aleksej Nikolaevich
RU2683691C1
METHOD FOR PREDICTING THE RISK OF THE UNFAVORABLE OUTCOME IN THE PATIENTS SUFFERING ISCHEMIC HEART DISEASE WITHIN THE YEAR FOLLOWING CORONARY ARTERIAL BYPASS 2019
  • Shlyk Irina Fedorovna
  • Sizyakina Lyudmila Petrovna
  • Sidorov Roman Valentinovich
  • Demidova Aleksandra Aleksandrovna
  • Shlyk Sergej Vladimirovich
RU2704956C1
METHOD FOR FORECASTING THE ONE-YEAR RISK OF DEVELOPMENT OF ADVERSE CARDIOVASCULAR EVENTS AFTER STENTING OF CORONARY ARTERIES IN PATIENTS WITH CORONARY HEART DISEASE WITH METABOLIC SYNDROME WITHOUT INSULIN RESISTANCE 2017
  • Teplyakov Aleksandr Trofimovich
  • Grakova Elena Viktorovna
  • Svarovskaya Alla Vladimirovna
  • Suslova Tatyana Evgenevna
  • Lavrov Aleksej Gennadevich
RU2663496C1
METHOD FOR STENT RESTENOSIS PREDICTION IN PATIENTS WITH ISCHEMIC HEART DISEASE 6 MONTHS AFTER CORONARY STENTING 2019
  • Shlyk Irina Fedorovna
  • Sizyakina Lyudmila Petrovna
  • Sidorov Roman Valentinovich
  • Demidova Aleksandra Aleksandrovna
  • Shlyk Sergej Vladimirovich
RU2695782C1
METHOD OF PREDICTION RISK OF ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS FOR 6 YEARS AFTER SCHEDULED ENDOVASCULAR MYOCARDIUM REVASCULARIZATION 2017
  • Vershinina Elena Olegovna
  • Lavrov Aleksej Gennadevich
  • Repin Aleksej Nikolaevich
RU2642930C1
METHOD OF PREDICTING THE RISK OF DEVELOPING CARDIOVASCULAR COMPLICATIONS IN PATIENTS WITH ABDOMINAL OBESITY WITH A STABLE COURSE OF CORONARY HEART DISEASE COMPLICATED BY CHRONIC HEART FAILURE II-III CLASS, WHO UNDERWENT MYOCARDIAL REVASCULARIZATION 2022
  • Poliakova Ekaterina Anatolevna
  • Sitnikova Mariia Iurevna
  • Galagudza Mikhail Mikhailovich
  • Shliakhto Evgenii Vladimirovich
RU2798728C1
METHOD OF PREDICTING RISK OF DEVELOPMENT OF ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH CORONARY HEART DISEASE AND TYPE 2 DIABETES WITH PRIOR CORONARY ARTERY STENTING 2015
  • Tepljakov Aleksandr Trofimovich
  • Kuznetsova Alla Vladimirovna
  • Grakova Elena Viktorovna
  • Protopopova Natalja Vsevolodovna
  • Andrijanova Anna Vladimirovna
  • Suslova Tatjana Evgenevna
RU2582291C1
METHOD FOR PREDICTING RISK OF DEVELOPING CARDIOVASCULAR COMPLICATIONS IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE, HAVING UNDERGONE PLANNED ENDOVASCULAR MYOCARDIAL REVASCULARIZATION 2021
  • Svarovskaia Alla Vladimirovna
  • Arzhanik Marina Borisovna
  • Garganeeva Alla Anatolevna
RU2770273C1

RU 2 799 146 C1

Authors

Lobe Aleksandra Ovanesovna

Ivanchenko Darya Nikolaevna

Dorofeeva Natalya Petrovna

Shlyk Sergej Vladimirovich

Demidova Aleksandra Aleksandrovna

Sizyakina Lyudmila Petrovna

Dates

2023-07-04Published

2022-07-13Filed