METHOD FOR ASSESSING THE RISK OF DEVELOPING ADVERSE OUTCOMES WITHIN THE FIRST YEAR FOLLOWING THE PERCUTANEOUS CORONARY INTERVENTION WITH STENTING IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE Russian patent published in 2019 - IPC G01N33/49 A61B10/00 

Abstract RU 2692257 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to cardiology, and can be used to predict the risk of adverse outcomes in patients with stable ischemic heart disease within 1 year after a percutaneous coronary intervention with stenting. Method comprises determining initial levels of interleukin-17 (IL-17) and interleukin-6 (IL-6) in blood serum by enzyme-linked immunosorbent assay, and then calculating risk of unfavorable outcomes by formula

,

where e is base of natural logarithm, e = 2.72, Z is calculated by formula Z = (-5.1 + (0.08) * x + (0.066) * y), x is content of IL-17 in blood serum in pg/ml, y – content of IL-6 in blood serum in pg/ml, and risk of developing adverse cardiovascular events is considered to be high while value K ≥ 0.13, and low – while K < 0.13.

EFFECT: use of the method enables higher accuracy of assessing the risk of unfavorable outcomes for 1 year after the percutaneous coronary intervention with stenting in the patients with stable coronary artery disease, which in turn will allow optimizing the therapeutic approach in these patients.

1 cl, 1 dwg, 3 tbl, 2 ex

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RU 2 692 257 C1

Authors

Orekhova Yuliya Nikolaevna

Ivanchenko Darya Nikolaevna

Demidova Aleksandra Aleksandrovna

Shlyk Sergej Vladimirovich

Sizyakina Lyudmila Petrovna

Dorofeeva Natalya Petrovna

Ter-Akopyan Aleksandra Ovanesovna

Chebotova Anastasiya Ivanovna

Dates

2019-06-24Published

2018-08-15Filed