FLEXIBLE POROUS SOLUBLE SOLID SHEET PRODUCTS WITH LARGE PORES AND METHOD FOR THEIR PRODUCTION Russian patent published in 2023 - IPC C08J5/18 C08J9/28 C08J9/30 C11D17/06 A61K8/02 

Abstract RU 2799326 C1

FIELD: chemistry.

SUBSTANCE: invention is related to a method for manufacturing a sheet product, comprised of the following steps: a) obtaining a wet premix containing a water-soluble polymer, which is polyvinyl alcohol, characterized by a degree of hydrolysis in the range from 40% to 100%, and one or more surfactants, and having a viscosity of 1000 cps to 25000 cps when measured at 40°C and 1 c-1 ; b) aerating the wet premix to form an aerated wet premix with a density of 0.05 to 0.5 g/ml; c) aging the aerated wet premix for at least 5 minutes; d) forming from said aerated wet premix a sheet with opposite first and second sides; and e) drying said formed sheet for a drying period of 1 minute to 60 minutes to produce a sheet product, the drying being carried out at a temperature of 70°C to 200°C along the heating direction which forms a temperature gradient decreasing from the first side to the second side of said shaped sheet, wherein said heating direction is opposite to the direction of gravity for more than half of the drying time.

EFFECT: improving the pore structures in flexible porous soluble sheets and improving their dissolution profile.

13 cl, 14 dwg, 21 tbl, 5 ex

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RU 2 799 326 C1

Authors

Mac Namara, Carl David

Tan, Hongsing

Glenn, Robert Wayne, Jr.

Tian, Xiao

Dates

2023-07-04Published

2019-11-29Filed