FIELD: biotechnology.
SUBSTANCE: invention relates to new conjugates of antibodies with drugs, and can be used in medicine. The invention discloses conjugates of antibodies capable of binding to tumor antigens with fragment-drugs that are splicing modulators, wherein the conjugated fragments are interconnected via a linker.
EFFECT: invention may be used in the treatment of neoplastic disorders, in particular cancer.
52 cl, 10 ex, 27 tbl, 26 dwg
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Authors
Dates
2023-07-05—Published
2019-05-31—Filed