THERAPEUTIC DRUG FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES AND ITS USE Russian patent published in 2023 - IPC A61K31/165 A61K31/216 A61K31/7008 A61K31/7024 A61P25/16 A61P25/24 A61P25/28 C07H13/02 C07H1/00 C07H15/20 

FIELD: pharmaceuticals.

SUBSTANCE: group of inventions relates to new therapeutic drugs for the treatment of neurodegenerative diseases, their production and use. A compound of formula I is proposed, as well as the use of a compound of formula I for the preparation of a drug for the prevention, alleviation or treatment of neurodegenerative diseases or depression, and a pharmaceutical composition containing the said compound and a pharmaceutically acceptable carrier. Also a method is provided for the prevention, alleviation or treatment of neurodegenerative diseases or depression, comprising administering to a subject in need thereof an effective amount of a compound of formula I or a pharmaceutically acceptable salt thereof, in particular compounds II, III, IV or V. Methods for preparing compounds III, IV or V are also provided. It has been shown that the compound of formula I can effectively enhance the functioning of neural stem cells in both in vivo and in vitro experiments, and can be used as part of a therapeutic approach to accelerate neuroregeneration to combat cognitive decline associated with the aging process or a neurodegenerative disease.

EFFECT: obtaining a therapeutic drug for the treatment of neurodegenerative diseases.

18 cl, 18 dwg, 18 ex