FIELD: chemical industry.
SUBSTANCE: invention relates to a method for producing diphenylphosphinylmethanehydrazide formula Ph2P(O)C(O)NHNH2. The method includes adding isobutyric aldehyde dimethyl acetal with cooling and stirring to a mixture of diphenylchlorophosphine and alkylchloromethane in toluene or without it, raising the temperature to room temperature and stirring until the diphenylchlorophosphine is completely consumed, removing volatile components by vacuum, adding benzene and cooling hydrazine to the formed alkyldiphenylphosphinylmethanoate and maintaining the reaction mixture at room temperature until the completion of the reaction.
EFFECT: improvement of the method for obtaining diphenylphosphinylmethanehydrazide due to in situ synthesis of O-methyldiphenylphosphinite and carrying out the synthesis in one boiler.
1 cl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
DIPHENYLPHOSPHINO METHANE HYDRAZIDE, WHICH HAS BIOLOGICAL ACTIVITY, AND THE METHOD FOR ITS PREPARATION | 2021 |
|
RU2783121C1 |
METHOD OF PRODUCING DIPHENYLPHOSPHINYLACETIC ACID HYDRAZIDE | 2023 |
|
RU2814311C1 |
[(4-DIMETHYLAMINOPHENYL)(2-CHLOROETHOXY)PHOSPHONYL]METHANE HYDRAZIDE, HAVING BIOLOGICAL ACTIVITY, AND METHOD FOR PRODUCTION THEREOF | 2024 |
|
RU2838153C1 |
METHOD FOR PREPARING N-DIPHENYLPHOSPHORYL-N′-ALKYL-(C-C)-UREAS | 2006 |
|
RU2296768C1 |
1-SULFONYL-2-(DIPHENYLPHOSPHORYL)PYRROLIDINES HAVING CYTOTOXICITY AGAINST CERVICAL CANCER CELLS, AND A METHOD OF PRODUCING SAID | 2020 |
|
RU2736205C1 |
AZO DERIVATIVES OF 5-AMINOSALICYLIC ACID, CAPABLE OF INHIBITING FORMATION OF END PRODUCTS OF GLYCATION | 2024 |
|
RU2837878C1 |
PHOSPHORYL-CONTAINING QUATERNARY AMMONIUM SALTS WITH HIGHER ALKYL SUBSTITUENTS WITH BACTERICIDAL AND FUNGICIDAL ACTIVITY | 2021 |
|
RU2770537C1 |
METHOD FOR PRODUCING BIS(3-AMINOPHENYL)PHOSPHENIC ACID TRIETHYLAMMONIUM SALT | 2017 |
|
RU2659033C1 |
METHOD OF OBTAINING3,3-DI(METHOXYCARBONYL)-1,5-DITHIACYCLOALKANES | 2012 |
|
RU2529503C2 |
METHOD OF PRODUCING TRIALKYL ESTERS OF PHOSPHOACETIC ACID | 2018 |
|
RU2678096C1 |
Authors
Dates
2023-07-14—Published
2023-01-12—Filed