METHOD OF PRODUCING FIBROBLASTS AND G-CSF-POSITIVE FIBROBLAST MASS Russian patent published in 2023 - IPC C12N5/77 A61K35/33 A61P9/00 

Abstract RU 2800644 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention provides a method of obtaining CD106 positive and/or CD90 positive fibroblasts. Also, the invention provides a cell population of G-CSF-positive fibroblasts and pharmaceutical compositions containing fibroblasts for the treatment of heart diseases.

EFFECT: method of obtaining CD106-positive and/or CD90-positive fibroblasts includes the step of culturing the fibroblasts in the presence of at least one factor selected from the group consisting of TNF-α and IL-4, with an increase in the number of CD106-positive and/or CD90-positive fibroblasts.

3 cl, 9 dwg, 11 tbl, 1 ex

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RU 2 800 644 C2

Authors

Ivamiya, Takakhiro

Osugi, Tomoyuki

Suzuki, Masaya

Dates

2023-07-25Published

2019-08-29Filed