FIELD: pharmaceuticals.
SUBSTANCE: invention provides a method of obtaining CD106 positive and/or CD90 positive fibroblasts. Also, the invention provides a cell population of G-CSF-positive fibroblasts and pharmaceutical compositions containing fibroblasts for the treatment of heart diseases.
EFFECT: method of obtaining CD106-positive and/or CD90-positive fibroblasts includes the step of culturing the fibroblasts in the presence of at least one factor selected from the group consisting of TNF-α and IL-4, with an increase in the number of CD106-positive and/or CD90-positive fibroblasts.
3 cl, 9 dwg, 11 tbl, 1 ex
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Authors
Dates
2023-07-25—Published
2019-08-29—Filed