FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine and deals with a composition for treating cardiac tissue, containing TGFβ-1, BMP4, α-thrombin, cardiotrophin and cardiogenol C, a method of obtaining differentiated cells-cardioprecursors from mammalian stem cells, including cultivation of initial cells in presence of the said composition; a method of providing cardiac tissue with cardiomyocytes, which includes introduction of differentiated cells, obtained by the method of obtaining described above, into cardiac tissue.
EFFECT: group of inventions ensures an improved specificity in a regulation of transcription of genes, required for differentiation induction.
27 cl, 23 dwg, 1 tbl, 3 ex
