FIELD: medicine.
SUBSTANCE: group of inventions relates to the treatment of Alzheimer's disease in an individual. The use of an agent for regulating the level of amino acids in the peripheral blood of a mammal for the manufacture of a medicament for the treatment of Alzheimer's disease in an individual is disclosed, where the amino acid is one or more selected from the following: 4-OH proline, acetylornithine, alanine, alpha-aminoadipic acid, asparagine, aspartic acid, asymmetric dimethylarginine, beta-alanine, carnosine, citrulline, creatinine, GABA, glutamic acid, glutamine, glycine, histidine, hypotaurine, isoleucine, kynurenine, leucine, lysine, methionine, methionine sulfoxide, ornithine, phenylalanine, pipecolic acid, proline, putrescine, pyroglutamic acid, serine, serotonine, taurine, threonine, tryptophan, tyrosine and valine. Also a method of screening a drug candidate that can be used to treat Alzheimer's disease and a method of treating a patient with Alzheimer's disease are disclosed.
EFFECT: expansion of the arsenal of means for a specific purpose.
17 cl, 23 dwg, 4 tbl, 4 ex
