CAPSID PROTEIN ASSEMBLY INHIBITOR CONTAINING N-HETEROCYCLIC FIVE-MEMBERED RING, ITS PHARMACEUTICAL COMPOSITION AND USE Russian patent published in 2023 - IPC C07D207/34 A61K31/40 A61P31/20 

Abstract RU 2802259 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound of formulas I and II or a pharmaceutically acceptable salt thereof, a pharmaceutical composition, use in the treatment of diseases in which a capsid protein assembly inhibitor is useful, in particular diseases caused by hepatitis B virus (HBV) infection.

EFFECT: new compounds of formulas I and II, effective inhibitors of capsid protein assembly, which can be useful for the treatment of diseases caused by hepatitis B virus (HBV) infection, have been obtained.

9 cl, 10 tbl, 6 ex

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Authors

Zhang Yinsheng

Ao Wangwei

Li Yuan

Wang Hui

Shen Hangzhou

Ni Jie

Zhang Huan

Wu Jie

Zhang Li

Cao Kai

Lu Peng

Liu Xushi

Wang Jie

Zhao Tianxiao

Ge Xingfeng

Lu Dandan

Chen Shuo

Ma Xueqin

Shi Wei

Wang Xiaojin

Xu Hongjiang

Dates

2023-08-24Published

2019-09-27Filed