FIELD: pharmaceuticals and medicine.
SUBSTANCE: 1 object is the use of a combination containing an antibody to CD19 and venetoclax in the treatment of a patient suffering from non-Hodgkin's lymphoma, chronic lymphocytic leukaemia and/or small cell lymphocytic lymphoma, where the specified antibody to CD19 is administered at least 7 days before the first administration of venetoclax. Object 2 - a method for the treatment of non-Hodgkin's lymphoma, chronic lymphocytic leukaemia and/or small cell lymphocytic lymphoma in a patient, including the introduction of a therapeutically effective amount of the combination.
EFFECT: reducing the risk of developing tumour lysis syndrome (TLS) during combined treatment.
36 cl, 3 dwg, 1 ex
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COMBINATION OF CD19 ANTIBODY AND BRUTON TYROSINE KINASE INHIBITOR AND THEIR APPLICATION | 2016 |
|
RU2756010C2 |
TYPES OF COMBINATION THERAPY USING CHIMERIC ANTIGEN RECEPTORS AND PD-1 INHIBITORS | 2017 |
|
RU2809160C2 |
FORMULATIONS BASED ON CD19 ANTIBODY | 2017 |
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RU2748024C2 |
NEW BISPECIFIC POLYPEPTIDE COMPLEXES AGAINST CD3/CD19 | 2018 |
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RU2788127C2 |
COMBINATION OF CELL THERAPY AND IMMUNOMODULATOR COMPOUND | 2018 |
|
RU2777911C2 |
ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SPECIFIC TO CD123 AND THEIR USE | 2018 |
|
RU2789150C2 |
METHODS AND COMPOSITIONS FOR ADMINISTRATION OF DOSES OF ALLOGENEIC T-CELLS WITH CHIMERIC ANTIGEN RECEPTOR | 2018 |
|
RU2776322C2 |
DOSING STRATEGY REDUCING CYTOKINE RELEASE SYNDROME FOR CD3/C20 BISPECIFIC ANTIBODIES | 2019 |
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Authors
Dates
2023-09-04—Published
2018-05-30—Filed