COMBINATION OF CD19 ANTIBODY AND BRUTON TYROSINE KINASE INHIBITOR AND THEIR APPLICATION Russian patent published in 2021 - IPC A61K31/505 A61K31/519 A61K39/395 A61P35/02 C07K16/28 

Abstract RU 2756010 C2

FIELD: immunology.

SUBSTANCE: use of a synergetic combination of CD19 antibody and ibrutinib is proposed. Besides, a method for the treatment is considered.

EFFECT: present invention can be further used in the therapy of non-Hodgkin lymphoma, chronic lymphocytic leukemia and acute lymphoblastic leukemia expressing CD19.

36 cl, 20 dwg, 18 tbl, 1 ex

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RU 2 756 010 C2

Authors

Endell Jan

Boxhammer Rainer

Winderlich Mark

Dates

2021-09-24Published

2016-05-25Filed