COMBINATION OF CD19 ANTIBODY WITH BCL-2 INHIBITOR AND ITS APPLICATION METHODS Russian patent published in 2021 - IPC C07K16/28 A61K31/496 A61K31/5377 A61K39/395 A61P35/02 

Abstract RU 2756405 C2

FIELD: immunology.

SUBSTANCE: use of a combination containing an antibody specific to CD19 and venetoclax in the treatment of non-Hodgkin’s lymphoma, chronic lymphocytic leukemia or acute lymphoblastic leukemia that express CD19 is proposed. In addition, a method for the treatment of non-Hodgkin’s lymphoma, chronic lymphocytic leukemia or acute lymphoblastic leukemia that express CD19 is considered.

EFFECT: this invention can find further application in the therapy of cancer expressing CD19.

38 cl, 10 dwg, 8 tbl, 2 ex

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RU 2 756 405 C2

Authors

Endell Jan

Petropoulos Konstantin

Kelemen Peter

Boxhammer Rainer

Ruckert Markus

Dates

2021-09-30Published

2017-10-27Filed