FIELD: medicine.
SUBSTANCE: invention relates to hybrid derivatives of ursolic and gallic acids comprising 1,2,3-triazole linkers, namely 3-(2-(4-((3β -acetoxyurs-12-ene)-28-ylaminomethyl)-1H-1,2,3-triazol-1-yl)ethoxy)-4,5-((R,S)-methoxymethylenedioxy)-benzoate 1а and 5-( ((1-(2-(3β -acetoxyurs-12-en-28-oylamino)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)carbonyl)-1,2,3 trihydroxybenzene 1b.
EFFECT: development of new effective agents with high antioxidant properties and anti-inflammatory activity based on available plant metabolites of ursolic acid and gallic acid.
1 cl, 3 dwg, 1 tbl, 14 ex
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