CRYSTAL FORM OF 6-METHYL-2-ETHYLPYRIDIN-3-OL MALATE AND PHARMACEUTICAL COMPOSITION AND A DRUG CONTAINING IT Russian patent published in 2023 - IPC C07D213/65 A61K31/4415 A61P9/10 A61P25/28 

Abstract RU 2803255 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a crystalline form of 6-methyl-2-ethylpyridin-3-ol malate characterized by the positions of the peaks in the powder X-ray pattern obtained using Cu(Kα)-radiation, 2θ, deg: 11.0± 0.2, 17.2± 0.2, 24.7± 0.2 and 26.0± 0.2. The invention also relates to a pharmaceutical composition and a medicinal product containing a crystalline form of 6-methyl-2-ethylpyridin-3-ol malate, as well as their use for the symptomatic treatment of neurological and mental diseases or disorders, circulatory disorders, as well as for improving cognitive abilities.

EFFECT: reduced hygroscopicity while maintaining good solubility and high stability of 6-methyl-2-ethylpyridin-3-ol salt, therapeutic efficacy for symptomatic treatment of neurological and mental diseases or disorders, circulatory disorders and improvement of cognitive abilities.

13 cl, 2 dwg, 3 tbl, 10 ex

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RU 2 803 255 C1

Authors

Golubeva Natalya Aleksandrovna

Dates

2023-09-11Published

2022-06-10Filed