FIELD: molecular biology; biochemistry; medicine; pharmacology.
SUBSTANCE: invention represents the use of (+)-usnic acid derivatives of formula I a–c as an agent for inhibiting reproduction of SARS-CoV-2 virus strains. I a–c.
EFFECT: invention provides effective reduction of SARS-CoV-2 virus titre (strains hCoV-19/Australia/VIC01/2020, hCoV-19/Russia/PSK-2804/2021, hCoV-19/Russia/Moscow171619-031221/2021, hCov-19/Russia/Moscow-49415/2022, hCoV-19/Russia/TOM-SRC-8663/2023, hCov-19/Russia/TYU-SRC-8642/2023) in cell culture.
2 cl, 1 dwg, 6 tbl, 13 ex
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