METHOD OF FUNCTIONALIZING SURFACE OF MEDICAL DEVICE BY INCLINED DEPOSITION OF STRUCTURED ANTIBACTERIAL COATING BASED ON CALCIUM PHOSPHATES Russian patent published in 2023 - IPC A61L27/12 A61F2/00 C23C14/35 

FIELD: medical equipment.

SUBSTANCE: invention relates to a method of functionalizing the surface of an implant by deposition of a structured antibacterial coating based on calcium phosphates. The method involves sputtering a target made of zinc- or copper-containing hydroxyapatite in the form of a flat disk 2–4.5 mm thick with a diameter coinciding with the diameter of the magnetron cathode, mounted on the magnetron cathode, in the plasma of a high-frequency (HF) magnetron discharge in an argon atmosphere when placing the implant on holder of the turntable of the vacuum chamber at a distance of 37–80 mm from the lower plane of the target. When forming the antibacterial coating of the implant, the vacuum chamber is evacuated to a residual pressure of not higher than 6.0*10^-4 Pa, then filled with argon and brought to the operating pressure (1.0–3.0)*10^-1 Pa, the RF magnetron discharge is ignited at power of 50 W, followed by a stepwise, at an interval of 50 W, increase in power to 200–300 W and holding for 10 minutes at each step, the process of RF magnetron sputtering of an antibacterial coating from the target is carried out, bringing the working pressure vacuum with the introduction of the implant into the magnetron zone and exposure in the magnetron zone. The deposition is inclined, the implant is placed on a holder with fixing elements capable of providing an inclination of the implant surface in an angle range of 40° up to 85° relative to the direction of the flow of flying particles during the formation of an antibacterial coating. The process of RF magnetron sputtering of the antibacterial coating from the target is carried out with the working pressure vacuum being brought to a value of (7.0–9.0)*10^-2 Pa, with the introduction of the implant into the magnetron zone and exposure in the magnetron zone for 4–8 hours.

EFFECT: production of an implant with a coating based on hydroxyapatite with zinc or copper ions by inclined deposition onto the surface of a metal or ceramic implant, which ensures the creation of conditions for effective healing of bone tissue and suppression of the risk of infection by pathogenic microorganisms due to the action of antibacterial ions and surface morphology features.

3 cl, 6 dwg