FIELD: pharmaceuticals.
SUBSTANCE: conjugate of Formula (Ic), including a ligand, a spacer and a peptide linker, useful for an in-vivo diagnostic agent and internal radiation therapy, using a Fab fragment of an antibody to human MUC1, the binding activity of which is not weakened even when labeled with a fluorescent metal dye or so.
biomolecule
EFFECT: diagnostic and pharmaceutical compositions intended for diagnosing or treating cancer expressing human MUC1 are provided.
31 cl, 3 dwg, 60 tbl, 10 ex
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