FIELD: biotechnology; medicine.
SUBSTANCE: invention discloses a conjugate in the molecule of which a Fab fragment of an anti-human MUC1 antibody and at least one fragment of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) are combined either through a linker or directly. The following is also disclosed: a chelate complex of the said conjugate with ions of a paramagnetic metal or radioisotope of a metal.
EFFECT: invention may be applicable for the diagnosis or treatment of cancer with cells express MUC1.
24 cl, 1 dwg, 5 tbl, 5 ex
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