FIELD: medicine.
SUBSTANCE: invention relates to phosphoryl-substituted 3-keto-androst-4-ene-[16,17-d]pyridazines of general formula I, where R=Ph, NHPh or NHtBu.
EFFECT: creation of new steroid compounds with high antiproliferative activity against hormone-dependent breast cancer cells MCF7 and triple-negative breast cancer cells MDA-MB-231, which can be used in medicine to create antitumor agents.
3 cl, 4 ex, 1 tbl
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