FIELD: pharmaceutical industry.
SUBSTANCE: invention relates to a wound healing composition. A hydrophilic composition for the treatment of wounds of various etiologies based on Kalanchoe pinnate juice is a viscous gel containing active components in the form of Kalanchoe pinnate juice, prepared by water extraction from hydroponically grown plant leaves, as a base and a set of excipients, according to the invention, Kalanchoe pinnate leaves grown hydroponically are cut and placed for 10 days in a dark place at a temperature of +2+8°C, then the leaves are crushed mechanically with the addition of distilled water in a 1:1 ratio to the crushed biomass, the mixture is left for 24 hours at a temperature of +2+8°C, after which the container with the mixture is left for 4 hours at a room temperature; next, the juice is filtered through an ash-free paper filter with a paper specific gravity of 80 g/m2 with an average pore size of 8–12 microns, and then the components are mixed at the following ratio, wt.%: 20.00–25.00 of Kalanchoe pinnate juice; 1.50–4.00 of glycerin; 1.00–1.50 of sodium salt of carboxymethylcellulose; 0.50–1.00 of sodium salt of hyaluronic acid with high molecular weight; 0.10–7.00 of excipients; up to 100.00 of purified water.
EFFECT: above-described composition is stable, has an increased therapeutic effect in the treatment of wounds, reduces side effects, and shortens wound healing time.
1 cl, 3 ex
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Authors
Dates
2023-11-21—Published
2023-01-24—Filed