FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, which may be useful as a THR receptor agonistβ. In formula (I), R1 is selected from the group consisting of hydrogen, cyano and C1-6 alkyl; R2 and R3 are each an independently selected halogen; ring A is a substituted or unsubstituted C5-10 aromatic ring, where the substituent is selected from the group consisting of hydrogen, halogen and C1-6 alkyl; and the halogen is selected from the group consisting of F, Cl and Br.
EFFECT: invention also relates to a pharmaceutical composition containing the said compound and its use for the manufacture of a therapeutic medicinal product for a thyroid hormone receptor beta-related metabolic disease.
(I)
21 cl, 3 tbl, 21 ex
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Authors
Dates
2023-12-06—Published
2019-12-12—Filed