FIELD: biotechnology.
SUBSTANCE: following is described: a group of inventions including a toxin conjugate having inhibitory activity against RNA polymerase, or a pharmaceutically acceptable salt thereof, an antitumor compound having inhibitory activity against RNA polymerase, including a toxin conjugate or a pharmaceutically acceptable salt thereof, and a method of using the toxin conjugate or a pharmaceutically acceptable salt thereof for producing an antitumor drug having RNA polymerase inhibitory activity.
EFFECT: invention expands the arsenal of agents that have inhibitory activity against RNA polymerase.
7 cl, 3 dwg, 2 tbl, 13 ex
| Title | Year | Author | Number |
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RU2792201C2 |
