COMPOSITION AND METHOD OF PREVENTION, REMOVAL OF SYMPTOMS OR THERAPEUTIC EFFECT ON LIVER DAMAGE Russian patent published in 2023 - IPC A61K35/742 A61P1/16 

FIELD: medicine.

SUBSTANCE: object 1 is the use of a strain of Ruminococcus faecis for the prevention, relief of symptoms or therapeutic effect on non-alcoholic fatty liver disease in a subject having insulin resistance, wherein the non-alcoholic fatty liver disease has one or more characteristics such as an increased concentration of ALT in the blood, an increased concentration of AST in the blood, decreased concentration of secondary bile acids in the cecum, increased expression of fibrotic genes Collal, Timp1 and α-SMA and increased liver weight to body weight ratio. Object 2 is a method of preventing, relieving symptoms or therapeutically affecting non-alcoholic fatty liver disease with the above characteristics in a subject with insulin resistance, comprising orally administering a strain of Ruminococcus faecis to the said subject.

EFFECT: therapeutic effect of the Ruminococcus faecis strain on non-alcoholic fatty liver disease in a subject with insulin resistance.

4 cl, 5 dwg, 5 tbl, 5 ex