COMPOSITION FOR PREVENTING, IMPROVING OR TREATING OBESITY OR FATTY LIVER DISEASE CONTAINING LEUCONOSTOC CITREUM WiKim0104 Russian patent published in 2024 - IPC C12N1/20 A61K35/744 A61P1/16 A61P3/04 

FIELD: medicine.

SUBSTANCE: invention relates to a Leuconostoc citreum WiKim0104 strain and use thereof. Presented is a Leuconostoc citreum WiKim0104 strain with identification number KCCM12420P intended for preventing, relieving or treating a disease associated with accumulation of fat in hepatocytes selected from inflammation, obesity or fatty liver disease. Also disclosed is the use of said strain or its culture to prevent, relieve or treat a disease associated with accumulation of fat in hepatocytes, selected from inflammation, obesity or fatty liver disease. Also disclosed is a composition containing said strain or culture thereof, and a method for preventing, relieving or treating a disease, associated with accumulation of fat in hepatocytes, selected from inflammation, obesity or fatty liver disease, involving administering said composition to a subject in need thereof.

EFFECT: invention provides inhibitory action on development of fatty liver disease by inhibiting fat accumulation in liver cells and reducing expression of genes associated with fatty liver disease.

12 cl, 4 dwg, 4 ex