FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a gadolinium-hexacid complex of formula (I), consisting of at least 80% diastereoisomeric excess of diastereoisomers I-RRR and I-SSS. Also the following is provided: a complex of formula (II) consisting of at least 80% diastereoisomeric excess of diastereoisomers II-RRR and II-SSS. The invention also relates to a method of preparing the said complex of formula (II) and an intermediate of formula (VI).
EFFECT: invention makes it possible to obtain a group of isomers, including a mixture of isomers II-RRR and II-SSS, which is thermodynamically stable and shows itself to be most advantageous as a contrast agent for medical imaging.
22 cl, 1 dwg, 6 tbl, 1 ex
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