FIELD: medicine, oncology.
SUBSTANCE: group of inventions discloses an antitumor combination containing the acid salt of chidamide and the basic salt of celecoxib, in which the acid salt of chidamide is a hydrochloride or sulfate salt. Also the following is disclosed: a method of regulating the tumor microenvironment during cancer immunotherapy, a method of treating cancer, and a method of treating cancer by regulating the tumor microenvironment and increasing the rate of formation of the immune response.
EFFECT: increase in the rate of formation of the immune response and antitumor activity.
31 cl, 5 tbl, 14 dwg, 10 ex
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