METHOD OF STABILIZING HUMIDOSENTIVE PHARMACEUTICAL SUBSTANCE AND ITS STABILIZED MEDICINAL PRODUCT Russian patent published in 2024 - IPC A61K31/513 A61K47/04 A61K47/38 A61P35/00 

FIELD: pharmaceutical technology.

SUBSTANCE: group of inventions relates to a capsule medicinal product for the treatment of cancer containing DFP-11207 and a method of producing this medicinal product. The capsule medicinal product for the treatment of cancer contains DFP-11207 or a pharmaceutically acceptable salt thereof in an amount from 25 to 63% by weight, microcrystalline cellulose in an amount from 35 to 73% by weight and colloidal silicon dioxide in an amount from 2 to 5% by weight. A method of producing a capsule medicinal product for the treatment of cancer includes filling of a capsule shell with DFP-11207 or its pharmaceutically acceptable salt in an amount from 25 to 63% by weight, microcrystalline cellulose in an amount from 35 to 73% by weight and colloidal silicon dioxide in an amount from 2 up to 5% by weight.

EFFECT: above-described group of inventions makes it possible to stabilize DFP-11207, which is a moisture-sensitive substance that is unstable at high humidity.

7 cl, 13 tbl, 2 ex