FIELD: pharmaceutical industry.
SUBSTANCE: invention relates to the use of a population of extracellular vesicles (EV) of plant origin in the therapeutic treatment of impaired angiogenesis. Use of a plant-derived population of extracellular vesicles (EVs) derived from a plant selected from the group consisting of orange, lemon, grapes, Anastatica hierochuntica (AH) and Selaginella lepidophylla (SL), wherein the extracellular vesicles (EVs) in the said population are confined to a lipid bilayer membrane and have a diameter ranging from 25 to 350 nm, and a protein content ranging from 1 to 55 ng/109 EV, in the therapeutic treatment of impaired angiogenesis.
EFFECT: above-described plant-derived vesicles used are effective for the therapeutic treatment of impaired angiogenesis.
8 cl, 19 dwg, 1 tbl, 11 ex
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