SUBSTITUTED 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES Russian patent published in 2024 - IPC C07D471/04 C07D487/04 C07D519/00 A61K31/519 A61K31/5383 A61P35/00 

Abstract RU 2812726 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound of formula (I), as well as a pharmaceutical composition based thereon for inhibiting WEE1 and methods of attenuating or treating cancer or attenuating or treating a malignancy or tumour by inhibiting WEE1.

EFFECT: obtaining new compounds that have the ability to inhibit WEE1 and can be used to treat a disease mediated by this activity.

32 cl, 42 ex, 1 tbl

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RU 2 812 726 C2

Authors

Khuan, Piter, Tsinkhua

Banker, Kevin, Duejn

Boren, Brant, Klejton

Khegde, Saji, Gadzhanan

Lyu, Khuej

Unni, Aditya, Krishnan

Abrakham, Sanni

Khopkins, Chad, Deniel

Palival, Sunil

Dates

2024-02-01Published

2019-02-26Filed