CD40L ANTAGONIST AND METHODS OF ITS USE Russian patent published in 2024 - IPC C07K14/47 A61K38/16 A61P37/06 A61P29/00 

Abstract RU 2812919 C2

FIELD: biotechnology.

SUBSTANCE: following is provided: methods of treating or preventing an autoimmune disease, comprising administering the CD40L-specific Tn3 scaffold protein at a dose of 500 mg to 3,000 mg to a subject in need thereof.

EFFECT: inventions are used for the treatment or prevention of such diseases as focal segmental glomerulosclerosis, systemic sclerosis, myositis, antiphospholipid syndrome, autoimmune hepatitis, lupus nephritis, idiopathic thrombocytopenic purpura, Sjogren's syndrome, IgG-related disease, erythematous lupus.

14 cl, 26 dwg, 2 tbl, 15 ex

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RU 2 812 919 C2

Authors

Drappa, Jorn

Albulescu, Marius

Li, Jing

Grant, Ethan

Streicher, Katie

Illei, Gabor

Wang, Liangwei

Rees, William

Dates

2024-02-05Published

2019-09-25Filed