METHOD OF TREATING SALMONELLOSIS IN YOUNG CATTLE Russian patent published in 2024 - IPC A61D99/00 A61K33/38 

FIELD: veterinary pharmacology.

SUBSTANCE: method of the treatment of salmonellosis in young cattle, including the introduction of polyvalent serum against salmonellosis, pasteurellosis, escherichiosis, parainfluenza-3 and infectious bovine rhinotracheitis, 10 cm³ of which contains effective titers of specific antibodies to Pasteurella multocida strains No. 8683, No. 656, No. T-80 — not less than 66%, to strains of Salmonella Typhimurium No. 371, Salmonella dublin No. 373 — not less than 80%, to strains of Escherichia coli 115/2 (O115), 320 (O78:K80) — not less than 70%, titers specific antibodies to Pasteurella haemolitica strain No. 169 in the RNGA — not less than 1:64, to Escherichia coli strains O115:K88, O141:K99, O9:K103:987P, 0141:F41 — producers of adhesive antigens: K88, K99, 987R, F41 in RA — not less than 1:400, to parainfluenza-3 virus in RTGA — not less than 1:128, and to infectious bovine rhinotracheitis virus — not less than 1:32, feeding in the amount of 19–20 cm³ of Argerit-40 antiseptic in the form of an aqueous solution of silver containing 0.8 mg of silver ions per 100 ml of water, an immunostimulating drug and intramuscular administration of a vitamin complex, characterized by additional using of the following: Lexoflon® antibiotic, which is administered intramuscularly at a dose of 5 cm per kilogram of animal weight, once a day for five days; Allervet 1% antihistamine, calves are injected intramuscularly with 0.025 cm³ per kilogram of animal weight twice a day once; to activate metabolic processes, it is administered intramuscularly twice a day at a dose of 10 cm³ per animal with an interval of five days — Catozal®; Calfoset is used as macro- and microelements®, which is administered once, intramuscularly 25 cm³ per animal, and Injection Multivitamin as a complex of vitamins in a dose of 5 cm³ per animal twice with an interval of ten days, while Argerit-40 antiseptic in the form of an aqueous solution of silver is provided as liquid in an amount of 19–20 cm³ per animal for 30 days, due to the fact that silver has a bactericidal effect, and polyvalent serum against salmonellosis, pasteurellosis, escherichiosis, parainfluenza-3 and infectious rhinotracheitis of cattle is administered in a dose of 60 cm³ with an interval of two days, and as an immunostimulating drug Kargmez aqueous-alcoholic herbal tincture is used, prepared from a herbal collection consisting of 2 parts of Echinacea purpurea, 1 part of St. John’s wort — leaves and flowers 0.5 parts each, 0.5 parts of nettle leaves and 0.5 parts of lemon balm — leaves and apical shoots 0.25 parts each, and 1 part of the herbal collection are mixed with 70 vol.% rectified ethyl alcohol in a ratio of 1:5 and 200 ml of Argerite-40 per 100 ml of water is added, then thermostated at a temperature of 36–37°C for 14 days, then the resulting tincture is brought to 30% concentration, diluting with distilled water, infused for 24 hours for better diffusion, diluted with 130–150 ml of boiled water and fed to the animal at a dose of 0.10–0.12 ml per 1 kg of its mass.

EFFECT: invention makes it possible to increase the effectiveness of treatment of young cattle.

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