AUTOMATED SYSTEM AND METHOD FOR LABORATORY MICROSCOPIC EXAMINATION OF MICROSLIDES Russian patent published in 2024 - IPC G01N33/483 G02B21/00 G06T1/40 

FIELD: measurement technology.

SUBSTANCE: group of inventions relates to an automated method for laboratory microscopic examination of microslides and a system for its implementation. Motorized table is automatically set to the base position. Table motors provide its automatic movement along the XY axes in the horizontal plane. Stage has a cassette with N slots for placing the microslides and can be connected to the place of the standard stage of the microscope. Table is automatically moved in the horizontal plane so that the center of the i-th microslide is located under the microscope objective. Motorized table is automatically moved by means of the Z-module in the vertical plane so as to focus the center of the i-th microslide. Z-module is configured to be attached to the focus handle of the microscope. Table is automatically displaced in the horizontal plane so that the microscope objective is located above the top of the object of analysis of the microslide at the boundary of the object of investigation/glass. Microscopic images of the analyzed object are obtained by snake motion scanning it during automatic movement of the motorized table in the horizontal plane. Obtained images are analyzed by a detection neural network and cells are detected on the obtained image until a given condition is achieved. Obtained analysis results are transmitted to a server for classification of the detected cells by types using a classification neural network. One proceeds with the next microslide. Steps 2 to 7 are repeated until analysis of all the microslides in the cassette of the motorized stage is completed.

EFFECT: enabling automation of laboratory microscopic examination of microslides with the possibility of analyzing several microslides simultaneously; the speed and accuracy of the analysis are also increased.

10 cl, 6 dwg, 4 tbl