METHOD OF THERAPY FOR COLORECTAL CANCER IN IN VIVO EXPERIMENT Russian patent published in 2024 - IPC A61N5/10 A61K31/375 A61P35/00 

Abstract RU 2814946 C1

FIELD: medicine; oncology.

SUBSTANCE: invention can be used in the treatment of colorectal cancer in an in vivo experiment. Mice are injected with 0.2 ml of a 120 mM sterile aqueous solution of lithium ascorbate intraperitoneally. 30 minutes after the injection, the tumour is locally exposed to X-ray radiation at a dose of 4 Gy with an intensity of 15 mGy/s. Then, on days 2, 4 and 6 after irradiation, 0.2 ml of a 120 mM sterile aqueous solution of lithium ascorbate is reintroduced intraperitoneally.

EFFECT: invention provides a significant reduction in colorectal cancer tumours in laboratory mice, which increases the effectiveness of radiation therapy.

1 cl, 1 tbl

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RU 2 814 946 C1

Authors

Plotnikov Evgenii Vladimirovich

Belousov Mikhail Valerevich

Tretiakova Mariia Sergeevna

Brazovskii Konstantin Stanislavovich

Dates

2024-03-06Published

2023-04-28Filed