FIELD: medicine; oncology.
SUBSTANCE: invention can be used in the treatment of colorectal cancer in an in vivo experiment. Mice are injected with 0.2 ml of a 120 mM sterile aqueous solution of lithium ascorbate intraperitoneally. 30 minutes after the injection, the tumour is locally exposed to X-ray radiation at a dose of 4 Gy with an intensity of 15 mGy/s. Then, on days 2, 4 and 6 after irradiation, 0.2 ml of a 120 mM sterile aqueous solution of lithium ascorbate is reintroduced intraperitoneally.
EFFECT: invention provides a significant reduction in colorectal cancer tumours in laboratory mice, which increases the effectiveness of radiation therapy.
1 cl, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| TUMOUR CELL RADIOSENSITIZATION METHOD | 2024 |
|
RU2834199C1 |
| RADIOSENSITIZER | 2019 |
|
RU2720455C1 |
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|
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| METHOD FOR THERMOCHEMORADIATION TREATMENT OF RECTAL CANCER | 2005 |
|
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| METHOD OF TREATING RECTAL CANCER | 2010 |
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|
RU2415670C2 |
| METHOD FOR COMPLEX TREATMENT OF COLORECTAL CANCER METASTASES TO THE LIVER | 2020 |
|
RU2759046C1 |
| METHOD OF TREATING RECTAL CANCER WITH SYNCHRONOUS REMOTE METASTASES | 2011 |
|
RU2453345C1 |
