BETA-LACTAMASE INHIBITORS AND THEIR USE Russian patent published in 2024 - IPC A61K31/439 A61P31/04 C07D471/08 

Abstract RU 2815314 C2

FIELD: medicine.

SUBSTANCE: invention relates to a method of treating a bacterial infection in a patient, including administering to a patient in need of such treatment a therapeutically effective amount of ethyl 3-(((((2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl)oxy)sulfonyl)oxy)-2,2-dimethylpropanoate or a pharmaceutically acceptable salt thereof and a therapeutically effective amount of a β-lactam antibiotic, wherein the bacteria causing the bacterial infection produce β-lactamase and whereβ-lactam antibiotic is ceftibuten.

EFFECT: development of a treatment method based on a new compound or its pharmaceutically acceptable salt and β-lactam antibiotic, which can be used in medicine to effectively treat bacterial infections.

1 cl, 79 ex

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RU 2 815 314 C2

Authors

Gordon, Erik, M.

Frojnd, Dzhon

Gellop, Mark, A.

Dankshn, Mettyu, Aleksandr, Dzhejms

Dates

2024-03-13Published

2018-05-02Filed