METHOD OF PREDICTING POSTOPERATIVE DELIRIUM IN CHILDREN DURING SURGICAL CORRECTION OF SEPTAL CONGENITAL HEART DEFECTS UNDER CONDITIONS OF ARTIFICIAL CIRCULATION Russian patent published in 2024 - IPC G01N33/68 A01B5/00 

FIELD: medicine; anaesthesiology and resuscitation.

SUBSTANCE: invention can be used to predict postoperative delirium in children during surgical correction of septal congenital heart defects under artificial circulation. The serum concentration of the combination of markers of brain damage is determined immediately after completion of cardiopulmonary bypass. When protein levels exceed S100β above 874.7 ng/ml, neuron-specific enolase above 35.79 ng/ml and glial fibrillary acidic protein above 0.1098 ng/ml, a high probability of postoperative delirium is predicted. The invention provides improved diagnostics of the presence of postoperative delirium and prophylaxis to prevent its occurrence. It also helps to take measures to improve the detection of delirium, especially its hypoactive form, in the form of increasing the frequency of testing the patient using the postoperative delirium rating scale.

EFFECT: possibility to make a decision on the initiation of cerebroprotective therapy.

1 cl, 2 ex