METHOD FOR PREDICTING NEUROLOGICAL RECOVERY FROM THE 14TH TO THE 90TH DAYS OF ISCHEMIC STROKE OF THE BRAIN Russian patent published in 2022 - IPC A61B5/1468 G01N33/48 G01N33/53 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to neurology, and can be used for prediction of neurological recovery of patients in period from 14th to 90th days of ischemic stroke of brain. For this purpose, on the 14th day of acute ischemic stroke, serum concentrations of the basic myelin protein (MBP), antibodies to it (anti-MBP), vascular endothelial growth factor (VEGF), brain neurotrophic factor (BDNF) are determined, functional independence on the Phekin scale (mRS) and neurological deficiency on the Stroke Scale (SSS) scale is evaluated. The probability of neurological recovery of F on the 90th day in accordance with the developed formula is then considered. If F > 0.5, a high probability of neurological recovery from the 14th to the 90th day of ischemic stroke is predicted, if F < 0.5, the patient is unlikely to be reduced.

EFFECT: method makes it possible to carry out combined assessment of activity of processes of neurogenesis and angiogenesis, protective-compensatory, humoral reactions and degree of damage of myelin sheath of corticospinal tracts and can be possible to solve the problem of dosed rehabilitation interventions in early recovery period of ischemic stroke, which is most sensitive from point of view of structural and synaptic neuroplasticity, and also allows to achieve regression of neurological deficiency and increase functional independence personalised for each patient.

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