FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and is a method of simulating induced abrachia on a chicken embryo, which consists in the introduction into a neural tube of a chicken embryo of a lipophilic siRNA to the Pax3 gene of 2'-O-methyl modification in a volume which provides filling of the neural tube, wherein the lipophilic siRNA is introduced during formation of 16 pairs of somites.
EFFECT: invention provides simulation of induced abrachia on chicken embryo.
1 cl, 5 dwg, 1 ex
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