FIELD: medicine.
SUBSTANCE: invention can be used for modelling congenital hip dislocation in a chick embryo. Lipophilic siRNA to the Pax3 gene is introduced into the neural tube of the chick embryo in a volume that ensures filling of the neural tube. The introduction of lipophilic siRNA is carried out during a 51 hour-incubation period.
EFFECT: method allows to create a model of induced congenital hip dislocation by introducing lipophilic siRNA to the Pax3 gene into the neural tube of a chick embryo during a 51 hour-incubation period.
1 cl, 5 dwg, 1 ex
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Authors
Dates
2023-03-15—Published
2022-07-11—Filed