FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and relates to a new strain of foot-and-mouth disease virus Aphtae epizooticae of genotype Asia-1/G-V, family Picornaviridae, genus Aphthovirus, deposited in Russian National Collection of Exotic types of foot-and-mouth disease virus and other animal pathogens (FGBI "ARRIAH") under registration number No. 443 - dep./22-77 - GKShM FGBU "VNIIZZh" strain "Azia-1/G-V/2006" of genotype Azia-1/G-V of foot-and-mouth disease virus. Presented strain is reproduced in transplantable cell cultures of Siberian ibex kidney (PSGK-30), porcine kidney (IB-RS-2), newborn Syrian hamster kidney (BHK-21). In transplantable suspension cell culture of Syrian hamster kidney BHK-21/SUSP/ARRIAH for 9.65±0.47 hours of incubation concentration of 146S component of the strain "Asia-1/G-V/2006" of the genotype of Asia-1/G-V of the foot-and-mouth disease virus has average values of 4.65±0.16 mcg/cm3 (83.10±0.75%), preserving the initial characteristics when passaging in a new transplantable suspension cell line BHK-21/SUSP/ARRIAH.
EFFECT: presented strain "Azia-1/G-V/2006" can be used for making biopreparations for diagnosis and specific prevention of foot-and-mouth disease of genotype Azia-1/G-V and for controlling antigenic activity of FMD vaccines.
1 cl, 1 dwg, 6 tbl, 8 ex
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