FIELD: biotechnology.
SUBSTANCE: invention concerns a new strain of foot-and-mouth disease virus Aphtae epizooticae of A/AFRICA/G-I genotype, Picornaviridae family, Aphthovirus genus, deposited in the All-Russian State Collection of Exotic Types of Foot-and-Mouth Disease Virus and Other Animal Pathogens (GKSM) FGBI "ARRIAH" under registration number No.410-dep/22-44 — GKShM FGBI "ARRIAH", "A/Tanzania/2013" strain of A/AFRICA/G-I genotype of foot-and-mouth disease virus. The presented strain is reproduced in transplanted cell cultures of Siberian Mountain Ibex Kidney (PSGK-30), Pig Kidney (IB-RS-2), and Newborn Syrian Hamster Kidney (ВНК-21). In a transplanted suspension culture of Syrian hamster kidney cells ВНК-21/SUSP/ARRIAN for 13.10± 0.66 hours of incubation, the concentration of the 146S component of "A/Tanzania/2013" genotype A of the foot and mouth disease virus has an average value of 2.14±0.14 mcg/cm21 (74.84±0.71%), retaining the original characteristics when passaged in ВНК-21/SUSP/ARRIAH cell culture.
EFFECT: presented strain can be used for the manufacture of biopreparations for the diagnostics and specific prevention of A/AFRICA/G-I genotype and to control the antigenic activity of FMD vaccines.
1 cl, 1 dwg, 4 tbl, 5 ex
| Title | Year | Author | Number |
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