FIELD: biotechnology.
SUBSTANCE: described is a group of inventions comprising a compound of general formula 4-O-(β-D-N-acetylmuramyl)-6-O-R-2,5-anhydro-D-mannose, where R is the residue of the capsular polysaccharide of S. Pneumoniae of any serotype, except for serotypes 1 and 3, use of said compound to produce polysaccharide-protein vaccines against S. Pneumoniae and a method of producing said compound. In one embodiment, the capsular polysaccharide residue is a capsular polysaccharide residue of the S. pneumoniae serotype 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 15F, 18C, 19F, 19A, 22F, 23A, 23F or 33F.
EFFECT: invention enables to obtain modified capsular polysaccharides of Streptococcus pneumoniae, which do not contain impurities of common polysaccharide antigen of pneumococci.
7 cl, 7 dwg, 1 tbl, 7 ex
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