FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, in particular to a method of producing C-thiomethylated pyrrole derivatives of general formula 1 or 2, where in formula 1 R = iso-C3H7, (CH2)2OH, n-C7H15, in formula 2 R = iso-C3H7, (CH2)2OH, (CH2)2SH. Method is characterized by that to preliminarily obtained at 25–30 °C for 15–20 minutes, mixture of 37% aqueous formaldehyde with pyrrole or 2-(benzpyrrol-3-yl)acetic acid is added to the corresponding thiol RSH, followed by stirring at 70 °C for 6 or 12 hours in a pyridine medium.
EFFECT: disclosed method is single-reactor and enables to obtain new pyrrole derivatives of general formula 1 or 2.
1 cl, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| TREATMENT OF HELICOBACTER PYLORI INFECTIONS WITH USE OF MTAN INHIBITORS | 2015 |
|
RU2663803C2 |
| METHOD OF PRODUCING SULFANYL DERIVATIVES OF ANTIPYRINE | 2020 |
|
RU2740911C1 |
| METHOD FOR PRODUCTION OF 2-FLUORINE-3-METHYLBUT-2-ENYL AMINE OR ITS HYDROCHLORIDE (VERSIONS) | 2016 |
|
RU2610281C1 |
| PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | 2015 |
|
RU2703402C2 |
| PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | 2015 |
|
RU2687160C2 |
| INDOLINE-SULPHONAMIDE COMPOUNDS | 2007 |
|
RU2402530C2 |
| 2,4,5-TRI(METHOXYPHENYL)CIS-IMIDAZOLINE AND METHOD FOR PRODUCTION THEREOF | 2019 |
|
RU2730497C1 |
| METHOD FOR OBTAINING SUBSTITUTED (E)-2-(3-(1H-PYRROL-2-YL)ALLYLIDENE)-1H-INDANE-1,3(2H)-DIONES, AND THEIR APPLICATION AS PHOTOSENSITIZERS FOR SOLAR BATTERIES | 2023 |
|
RU2812075C1 |
| IMIDAZOPYRIDIN-2-ONE DERIVATIVES, HAVING mTOR INHIBITING ACTIVITY | 2009 |
|
RU2478636C2 |
| SULPHO-DERIVATIVES BASED ON BETA-PINENE AND A METHOD FOR PRODUCTION THEREOF | 2019 |
|
RU2708617C1 |
