2,4,5-TRI(METHOXYPHENYL)CIS-IMIDAZOLINE AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2020 - IPC C07D233/22 A61K31/4164 A61P35/00 

Abstract RU 2730497 C1

FIELD: chemistry.

SUBSTANCE: invention relates to cis-imidazoline derivatives of general formula I, in which R = 2-methoxyphenyl, 3-methoxyphenyl, 4-ethoxyphenyl, 2,3-dimethoxyphenyl, 3,4-dimethoxyphenyl, 2,5-dimethoxyphenyl, 2,4-dimethoxyphenyl, 3,4,5-trimethoxyphenyl, 3-methoxy-4-ethoxyphenyl or 3-methoxy-2-ethoxyphenyl. Invention also relates to an active component and a method of producing a compound of general formula I.

.

EFFECT: technical result is obtaining novel cis-imidazoline derivatives of general formula I, having inhibitory action on cell growth of non-small-cell lung cancer.

6 cl, 1 tbl, 11 ex

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RU 2 730 497 C1

Authors

Bazanov Daniil Romanovich

Lozinskaya Natalya Aleksandrovna

Pervushin Nikolaj Viktorovich

Kopeina Gelina Sergeevna

Anikina Lada Vladimirovna

Savitskaya Viktoriya Yurevna

Maksutova Anita Irekovna

Dates

2020-08-24Published

2019-07-31Filed