FIELD: medicine, pharmacology.
SUBSTANCE: invention relates to use of a compound - a pyrrolo[3,2,1-ij]quinolin-1-ylidene-2-thioxothiazolidin-4-one derivative of formula (I) as inhibitors of blood coagulation factors Xa and XIa. In general formula (I) R1 is a substitute selected from hydrogen; alkyl (C1-C2); phenyl without substitutes or substituted with halogen at position 4; R2 is a substitute selected from hydrogen; halogen; alkyl (C1-C2); alkoxy group (C1-C2); benzoyloxy without a substitute or substituted with a methoxy group at positions 3,4,5; R3 is a substitute selected from hydrogen; or alkyl (C1-C2); R4 is methyl; R5 is methyl; or R4+R5=(CH2)n, where n is integers 4, 5, 6.
EFFECT: implementation of the purpose.
1 cl, 3 dwg, 16 ex
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