FIELD: chemistry.
SUBSTANCE: group of inventions relates to chemiluminescent substrates and includes compounds of formulas (I-3) and (I-4), acid addition salts thereof, combinations for measuring chemiluminescence, containing them, method for quantitative analysis of coagulation factor in sample and method for quantitative analysis of anticoagulant in sample. In formulas (I-3) and (I-4), r is 0, 1, 2 or 3; r' is 0, 1, 2 or 3; d is 0, 1 or 2; g is 0 or 1; g' is 1; X is a terminal residue selected from OH, O(C1-6-alkyl), (OCH2CH2)1-6OH, (OCH2CH2)1-6O(C1-6-alkyl), NHC(=O)(O)0-1(C1-6-alkyl), NHC(=O)(O)0-1(C1-6-alkylene)(OCH2CH2)1-6OH, NHC(=O)(O)0-1(C1-6-alkylene)(OCH2CH2)1-6O(C1-6-alkyl), NHC(=O)(O)0-1(C1-6-alkylene)O(C1-6-alkyl), NHC(=O)(O)0-1(C1-6-alkylene)OH.
EFFECT: compounds of formulas (I-3) and (I-4) as chemiluminescent substrates for measuring blood coagulation factors.
19 cl, 20 dwg, 14 tbl, 7 ex
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